Eli Grushka
10/25/2006
Describes methods
for improving
the thermodynamic
and kinetic performance of stationary phasesDetails the use of affinity capillary electrophoresis for analyzing small molecules under high-throughput conditions Discusses the advantages of using ionic liquids as solvents and aptameters as affinity reagentsProvides combinatorial library design strategies to facilitate high-throughput purification methods Explores the potential of applying comprehensive 2D-GC to clinical, pharmaceutical, biological, and food analysisReviews recent results of chromatographic analyses of the various organic compounds suspected to be endocrine disrupters Discusses minimum requirements for utilizing readily available instrumentation and methods for new
applicationsFor more than four decades, scientists and researchers have relied on the
Advances in
Chromatography series for the most up-to-date information on a wide range of developments in chromatographic methods and applications.
Volume 45 of this authoritative series once again compiles the work of expert contributors in order to present timely and cutting-edge reviews on a variety of related topics.
This volume focuses on applying various chromatographic techniques to combinatorial methods and high-throughput analyses. The authors address various limitations to traditional techniques and present developments that enable scientists to analyze a higher volume of smaller molecules under high-throughput conditions more efficiently. Other practical topics include discussions of selection criteria for using alternative solvents and reagents, minimum requirements for utilizing readily available instrumentation and methods for new applications, the use of high-throughput purification for obtaining higher quality leads, and new chromatographic data on organic endocrine disrupters.
Advances in Chromatography: Volume 45 provides a good starting point to gain quick and up-to-date knowledge of the field and its most recent developments. Each author's clear presentation of topics and vivid illustrations make the material accessible and engaging to a variety of chemists
with different levels of technical skill.
Table of ContentsThe Thermodynamic and Kinetic Basis of Liquid Chromatography; X. Li, A.M. Hupp, and V.L. McGuffin
Applications of Ionic Liquids in Extraction, Chromatography, and Electrophoresis; C.F. Poole
Applications of Capillary Electrophoresis to
Molecular Recognition and
Analysis of In-Capillary Enzyme-Mediated Transformations; J. Zavaleta, D.B. Chinchilla, A. Brown, A. Ramirez, V. Calderon, T. Sogomonyan, R. Montes, and F.A. Gomez
Aptamers as Molecular Recognition Elements in Chromatographic Separations; D. Hutanu and V.T. Remcho
Advances in High-Throughput High-Performance Liquid Chromatography and "Purification-Friendly" Combinatorial Library Design Strategies; S. Schefzick
Biological, Clinical, and Forensic Analysis Using Comprehensive Two-Dimensional
Gas Chromatography; N.H. Snow
Determination of Endocrine Disrupting Chemicals Found in
Environmental Samples by Gas Chromatography/ Mass Spectrometry; J.D. Stuart
Index
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