Eli Grushka 9/26/2005 Search this book Conveys the enormous potential, versatility, and challenges of the multi-channel microchip concept and its applications in cellular biology and genomic sequencingDescribes multiple-channel microchip designs, substrates, sample loading, detection methods, and applicationsDiscusses the increasingly popular use of temperature in chromatographic separationDetails the use of different separation techniques for determining the lipophilicity of analytesCovers HPLC, TLC, counter current chromatography, micellar electrokinetics chromatography, and centrifugal partition chromatographyExplains how high performance liquid chromatography (HPLC) can be used in controlling the quality of the pharmaceutical productPresents polysaccharide CSPs in terms of their mechanisms of action and interaction with enantiomeric analytesIllustrates the effects of chaotropic agents in reversed-phase HPLC Highlights the challenges presented by the separation of water insoluble proteinsIncludes extensive, up-to-date references for further reference
For more than four decades, scientists and researchers have relied on the Advances in Chromatography series for the most up-to-date information on a wide range of developments in chromatographic methods and applications. Volume 44 of this authoritative series once again compiles the work of expert contributors in order to present timely and cutting-edge reviews on a variety of related topics.
Each author's clear presentation of topics and vivid illustrations make the material in Advances in Chromatography: Volume 44 accessible and engaging to biochemists and analytical, organic, polymer, and pharmaceutical chemists at all levels of technical skill.
Search this book Table of Contents SEPARATIONS IN MULTIPLE-CHANNEL MICROCHIPS T.L. Paxon and A.G. Ewing TEMPERATURE EFFECTS IN LIQUID CHROMATOGRAPHY E. Lundanes and T. Greibrokk LIPOPHILICITY MEASUREMENTS BY LIQUID CHROMATOGRAPHY S. Gocan. G. Cimpan, and J. Comer CONCEPTS AND PRACTICE OF MULTIDIMENSIONAL HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY R.A. Shalliker and M.J. Gray HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY IN THE PHARMACEUTICAL INDUSTRY: APPLICATION, VALIDATION, AND REGULATORY ISSUES M. Dantus THE USE OF POLYSACCHARIDE PHASES IN THE SEPARATION OF ENANTIOMERS R.W. Stringham CHAOTROPIC EFFECTS IN RP-HPLC R. LoBrutto and Y.V. Kazakevich CHROMATOGRAPHY OF DIFFICULT AND WATER-INSOLUBLE PROTEINS WITH ORGANIC SOLVENTS A.J. Alpert