Joel K. Swadesh 12/21/2000 Search this book Presents highly conceptual information in plain language, making it accessible to students and easy to read for experienced scientists Includes a comprehensive review of HPLC literature, eliminating the need for multiple references Provides extensive indexing and a careful structure to facilitate rapid answers to urgent problems Integrates important non-technical issues with the realities of the workplace, including discussion of a range of topics, from management theory to regulatory considerations and ethicsNew in the SecondEdition:Updates of all major topics highlighting recent literature and new developmentsExpanded discussion of mass spectroscopy, electrophoretic separations, and ultra-micro separationsFurther discussion on the nature and future of industrial development
Product specifications, regulatory constraints, and tight production schedules impose considerable pressures on separation scientists in industry. The first edition of HPLC: Practical and Industrial Applications helped eliminate the need for extensive library or laboratory research when confronting a problem, an unfamiliar technique, or work in a new area. Its plain language, comprehensive coverage of separation topics, and practical organization made it an accessible and convenient reference manual for anyone working in or just entering the field.
Since its publication in 1997, however, much has changed. The areas of mass spectroscopy, electrophoretic separations, and ultra-micro separations have blossomed, focus on quality control has intensified, and the literature has grown significantly. The Second Edition incorporates all of these changes and more. It is now fully current, with chapter supplements that include updated references and discussions of techniques.
This book examines analytical HPLC as it is actually used in industry. Whether you are just entering industry, switching from one industry to another, or simply enjoy understanding how things are made, HPLC: Practical and Industrial Applications will help you solve problems and get up to speed in new areas quickly, comfortably, and with a genuine sense of mastery.
Search this book Table of Contents INTRODUCTION, Jeffrey R. Larson, James E. Tingstad, and Joel K. Swadesh Overview Pumps Columns Chromatographic modes Detectors Chromatographic theory Laboratory operations The role of laboratory management AUTOMATED SAMPLING IN THE PROCESS ENVIRONMENT, Jeffrey R. Larson Issues in process HPLC Case histories Future directions for on-line HPLC process monitors Summary CHROMATOGRAPHY IN PROCESS DEVELOPMENT, Patricia Puma Scope of process chromatography Special hardware requirements Validation considerations Case history Summary REVERSED PHASE HPLC, Rekha D. Shah and Cynthia A. Maryanoff Introduction Chromatographic practice in RPLC Selected applications Case history: optimizing a chemical synthesis by RPLC Conclusions ION EXCHANGE CHROMATOGRAPHY, Joel K. Swadesh Introduction Ion exchange stationary phases Electrochemical detectors Applications Case history: isolation and partial characterization of hementin, a compound of biopharmaceutical interest Acknowledgments GEL PERMEATION CHROMATOGRAPHY, Rajesh G. Beri, Laurel S. Hacche, and Carl F. Martin Introduction Detectors for gel permeation chromatography Application of aqueous size-exclusion chromatography352 to carbohydrates: a case history HIGH PERFORMANCE CAPILLARY ELECTROPHORESIS: AN OVERVIEW, K醠m醤 Benedik and Andr醩 Guttman Introduction Fundamentals Instrument Separation modes Applications Conclusions Index
