Stem Cells and Cell Signalling in Skeletal Myogenesis (Advances in Developemental Biology & Biochemistry)
By
D.A. Sassoon
- Publisher: Elsevier Science
- Number Of Pages: 152
- Publication Date: 2002-02-08
- ISBN-10 / ASIN: 0444506632
- ISBN-13 / EAN: 9780444506634
- Binding: Hardcover
Book Description:
Skeletalmuscle development is perhaps one of the best understood processes atthe molecular, cellular and organismal level due in large part to thefact that primary myogenic cells (myoblasts) will grow and subsequentlydifferentiate into myotubes in culture. With the advent of reversemouse genetics, many of the observations gained through the study ofmyogenic cells in vitro have been directly tested in vivo. What hasemerged is a complex but cohesive story of how myogenic cells areinitially specified in the vertebrate embryo and how muscle fibersultimately achieve their respective identities (i.e. fast versus slow)to perform their function. This collection of chapters is focused onthese developments. The book discusses old and new directions for theskeletal muscle field and points out directions where the field mayeventually progress.
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