by Adrian T. Sumner
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Chromosomes: Organization and Function By Adrian T. Sumner
Product Description: Integratingclassical knowledge of chromosome organisation with recent molecularand functional findings, this book presents an up-to-date view ofchromosome organisation and function for advanced undergraduatestudents studying genetics. The organisation and behaviour ofchromosomes is central to genetics and the equal segregation of genesand chromosomes into daughter cells at cell division is vital. Thistext aims to provide a clear and straightforward explanation of thesecomplex processes. Following a brief historical introduction, the text covers the topics of cell cycle dynamics and DNAreplication; mitosis and meiosis; the organisation of DNA intochromatin; the arrangement of chromosomes in interphase; euchromatinand heterochromatin; nucleolus organisers; centromeres and telomeres;lampbrush and polytene chromosomes; chromosomes and evolution;chromosomes and disease, and artificial chromosomes. Topics areillustrated with examples from a wide variety of organisms, including fungi,plants, invertebrates and vertebrates. This book will be valuableresource for plant, animal and human geneticists and cell biologists. Originallya zoologist, Adrian Sumner has spent over 25 years studying human andother mammalian chromosomes with the Medical Research Council (UK). Oneof the pioneers of chromosome banding, he has used electron microscopyand immunofluorescence to study chromosome organisation and function,and latterly has studied factors involved in chromosome separation atmitosis. Adrian is an Associate Editor of the journal ChromosomeResearch, acts as a consultant biologist and is also Chair of theCommittee of the International Chromosome Conferences.
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